Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS8 | Q16651 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 18/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711269 | 0.86 | CMA1 (0.49) | CTSS | |
| SCHEMBL5711191 | 0.85 | PRSS1 (0.44) | — | |
| SCHEMBL5711290 | 0.81 | PRSS8 (0.49) | PRSS8CTSSCYP3A4CYP2C9 | |
| SCHEMBL7661082 | 0.73 | CMA1 (0.44) | CTSS | |
| SCHEMBL5711400 | 0.72 | CAPN1 (0.39) | CYP3A4 | |
| SCHEMBL5711349 | 0.72 | CMA1 (0.50) | — | |
| SCHEMBL7668464 | 0.72 | CMA1 (0.44) | — | |
| SCHEMBL5711189 | 0.71 | CMA1 (0.49) | — | |
| SCHEMBL5711368 | 0.69 | CMA1 (0.51) | — | |
| SCHEMBL5711366 | 0.69 | CMA1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |