SCHEMBL5711487

SCHEMBL5711487

C=C(C)C(=O)OC(CCC)[Si](OCC)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
THRB P10828 1/20 0.36
TSHR P16473 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537247 0.90 TSHR (0.40) ALDH1A1THRBTSHR
SCHEMBL29005268 0.89 TSHR (0.42) THRBTSHR
SCHEMBL11740826 0.89 TSHR (0.38) ALDH1A1THRBTSHR
SCHEMBL28358110 0.88 TSHR (0.45) THRBTSHR
SCHEMBL14936193 0.88 TSHR (0.45) THRBTSHR
SCHEMBL4600145 0.88 TSHR (0.45) THRBTSHR
SCHEMBL25276153 0.86 THRB (0.38) ALDH1A1THRBTSHR
SCHEMBL138292 0.86 THRB (0.38) ALDH1A1THRBTSHR
SCHEMBL11740485 0.86 TSHR (0.42) ALDH1A1THRBTSHR
SCHEMBL16537348 0.85 ALDH1A1 (0.35) ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113354783-A Toughened thermoplastic material and preparation method and application thereof 中国科学院化学研究所 2021-09-07 CN disclosed
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed
EP-1464514-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-12-27 EP disclosed
US-4029842-A POLYMETHYL METHACRYLATE COATED AND OVERCOATED WITH TRIALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-06-14 US disclosed