Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546506 | 0.82 | KMT2A (0.48) | KMT2ATSHRTDP1NPC1PKM | |
| SCHEMBL29768673 | 0.81 | KMT2A (0.47) | KMT2ATSHRTDP1NPC1PKM | |
| SCHEMBL9383147 | 0.79 | KAT2B (0.49) | KMT2ATSHRTDP1NPC1PKM | |
| SCHEMBL29596884 | 0.78 | KMT2A (0.47) | KMT2ATSHRTDP1NPC1PKM | |
| SCHEMBL10480634 | 0.78 | KAT2B (0.48) | KMT2ATSHRTDP1NPC1PKM | |
| SCHEMBL8797902 | 0.77 | ALDH1A1 (0.43) | KMT2ATSHRTDP1NPC1PKM | |
| SCHEMBL9820263 | 0.77 | NPC1 (0.45) | KMT2ATSHRTDP1NPC1PKM | |
| SCHEMBL108393 | 0.76 | KMT2A (0.65) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL29390080 | 0.76 | KMT2A (0.65) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL6896833 | 0.74 | KMT2A (0.62) | KMT2ATSHRTDP1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | claimed |