Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29768673 | 0.84 | KMT2A (0.47) | ALDH1A1KMT2ATSHRTDP1RAB9A | |
| SCHEMBL8799644 | 0.83 | GLA (0.38) | ALDH1A1KMT2APOLBMAPTPKM | |
| SCHEMBL8798677 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KMT2ATSHRTDP1POLB | |
| SCHEMBL6546506 | 0.77 | KMT2A (0.48) | ALDH1A1KMT2ATSHRTDP1RAB9A | |
| SCHEMBL5711652 | 0.77 | KMT2A (0.48) | ALDH1A1KMT2ATSHRTDP1RAB9A | |
| SCHEMBL29596884 | 0.76 | KMT2A (0.47) | ALDH1A1KMT2ATSHRTDP1RAB9A | |
| SCHEMBL9383147 | 0.74 | KAT2B (0.49) | ALDH1A1KMT2ATSHRTDP1RAB9A | |
| SCHEMBL8798720 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KMT2APOLBMAPTPKM | |
| SCHEMBL10480634 | 0.72 | KAT2B (0.48) | ALDH1A1KMT2ATSHRTDP1RAB9A | |
| SCHEMBL5690966 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KMT2ATSHRTDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532039-B1 | N1-trifluoroalkyl substituted 2-nitro-p-phenylenediamine dyes | BRISTOL MYERS SQUIBB CO (US) | 1997-12-03 | — | — | EP | claimed |
| EP-0532039-A1 | N1-trifluoroalkyl substituted 2-nitro-p-phenylenediamine dyes | Bristol-Myers Squibb Company (US) | 1993-03-17 | — | — | EP | claimed |
| EP-0532039-B1 | N1-trifluoroalkyl substituted 2-nitro-p-phenylenediamine dyes | BRISTOL MYERS SQUIBB CO (US) | 1997-12-03 | — | — | EP | disclosed |
| EP-0802916-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC (CA) | 1997-10-29 | — | — | EP | disclosed |
| EP-0532039-A1 | N1-trifluoroalkyl substituted 2-nitro-p-phenylenediamine dyes | Bristol-Myers Squibb Company (US) | 1993-03-17 | — | — | EP | disclosed |