Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.64 |
| ▸ | HPGD | P15428 | 11/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711760 | 0.94 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL7373916 | 0.77 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7373108 | 0.76 | TDP1 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL27522882 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL30885344 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL3640667 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL15820245 | 0.73 | POLB (0.54) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL14040562 | 0.73 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL6822984 | 0.73 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL7373427 | 0.72 | ACHE (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582198-B1 | Substituted (hetero-)aryle compounds, process for their preparation, those containing compositions and their use as safeners | BAYER CROPSCIENCE GMBH (DE) | 2006-02-08 | — | — | EP | claimed |
| EP-0582198-B1 | Substituted (hetero-)aryle compounds, process for their preparation, those containing compositions and their use as safeners | BAYER CROPSCIENCE GMBH (DE) | 2006-02-08 | — | — | EP | disclosed |
| US-6482947-B1 | Substituted (hetero) aryl compounds, process for their preparation, agents containing them and their use as safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 2002-11-19 | — | — | US | disclosed |
| US-5739079-A | CEREAL, RICE, CORN CROP SAFENER MIXED WITH WEED HERBICIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| EP-0582198-A2 | Substituted (hetero-)aryle compounds, process for their preparation, those containing compositions and their use as safeners | Hoechst Schering AgrEvo GmbH (DE) | 1994-02-09 | — | — | EP | disclosed |