Sugi Predict

Sugi Predict / Compounds / SCHEMBL5711786

SCHEMBL5711786

SCHEMBL5711786

CCCCC1(CC)C(=O)Sc2cc(OCC(=O)N[C@@H](C(=O)NCCN(C(N)=O)c3ccccn3)c3ccccc3)c(SC)cc2N(c2ccccc2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NR1H4 Q96RI1 1/20 0.39
▸ ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6205982 0.89 NR1H4 (0.39) NR1H4ELANE
SCHEMBL5721660 0.87 NR1H4 (0.45) NR1H4ELANE
SCHEMBL5815802 0.86 NR1H4 (0.40) NR1H4ELANE
SCHEMBL4654280 0.86 NR1H4 (0.41) NR1H4ELANE
SCHEMBL3835251 0.85 NR1H4 (0.44) NR1H4ELANE
SCHEMBL5689568 0.85 NR1H4 (0.42) NR1H4ELANE
SCHEMBL5709264 0.85 NR1H4 (0.42) NR1H4ELANE
SCHEMBL4624338 0.85 NR1H4 (0.40) NR1H4ELANE
SCHEMBL4598886 0.84 NR1H4 (0.43) NR1H4ELANE
SCHEMBL3836167 0.84 NR1H4 (0.45) NR1H4ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1699759-A1 DIPHENYLAZETIDINONE DERIVATES POSSESSING CHOLESTEROL ABSORPTION INHIBITORY ACTIVITY AstraZeneca AB (SE) 2006-09-13 — — EP disclosed
WO-2005061452-A1 DIPHENYLAZETIDINONE DERIVATES POSSESSING CHOLESTEROL ABSORPTION INHIBITORY ACTIVITY ASTRAZENECA AB (SE) 2005-07-07 — — WO disclosed