Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 3/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654280 | 0.94 | NR1H4 (0.41) | NR1H4ELANECTSD | |
| SCHEMBL5721660 | 0.89 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL3835251 | 0.87 | NR1H4 (0.44) | NR1H4ELANECTSD | |
| SCHEMBL5689568 | 0.87 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL5709264 | 0.87 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL5711786 | 0.86 | NR1H4 (0.39) | NR1H4ELANE | |
| SCHEMBL4598886 | 0.86 | NR1H4 (0.43) | NR1H4ELANECTSD | |
| SCHEMBL3836167 | 0.86 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4624338 | 0.86 | NR1H4 (0.40) | NR1H4ELANECTSD | |
| SCHEMBL4665640 | 0.85 | NR1H4 (0.44) | NR1H4ELANECTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102674-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2006-09-28 | — | — | WO | disclosed |