SCHEMBL571203

SCHEMBL571203

O=C1Cc2cccc3ccc4cccc1c4c23

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.85
HPGD P15428 4/20 0.85
KDM4E B2RXH2 3/20 0.85
CYP3A4 P08684 3/20 0.61
TSHR P16473 3/20 0.61
TYMS P04818 5/20 0.47
HSD17B10 Q99714 4/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 1/20 0.47
PARP1 P09874 2/20 0.46
BCHE P06276 2/20 0.45
CES1 P23141 2/20 0.45
CES2 O00748 1/20 0.45
MCL1 Q07820 1/20 0.45
PABPC1 P11940 2/20 0.39
DNMT1 P26358 2/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975376 0.92 ALDH1A1 (1.00) ALDH1A1HPGDKDM4ECYP3A4TSHR
SCHEMBL29383750 0.92 ALDH1A1 (1.00) ALDH1A1HPGDKDM4ECYP3A4TSHR
SCHEMBL254908 0.81 ALDH1A1 (0.72) ALDH1A1HPGDKDM4ECYP3A4TSHR
SCHEMBL27801274 0.80 ALDH1A1 (0.78) ALDH1A1HPGDKDM4ECYP3A4TSHR
SCHEMBL598499 0.78 TSHR (1.00) ALDH1A1HPGDKDM4ECYP3A4TSHR
SCHEMBL30352929 0.78 TSHR (1.00) ALDH1A1HPGDKDM4ECYP3A4TSHR
SCHEMBL21969015 0.76 ALDH1A1 (0.59) ALDH1A1HPGDKDM4ECYP3A4TSHR
SCHEMBL30001721 0.75 TSHR (0.94) ALDH1A1HPGDKDM4ECYP3A4TSHR
SCHEMBL4846405 0.75 TSHR (0.94) ALDH1A1HPGDKDM4ECYP3A4TSHR
SCHEMBL29862055 0.75 KDM4E (0.59) ALDH1A1HPGDKDM4ECYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012017977-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CANON KABUSHIKI KAISHA (JP) 2012-02-09 WO disclosed