SCHEMBL975376

SCHEMBL975376

O=C1Cc2cccc3cccc1c23

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
KDM4E B2RXH2 4/20 1.00
HPGD P15428 3/20 1.00
TYMS P04818 5/20 0.55
HSD17B10 Q99714 3/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C19 P33261 1/20 0.55
CYP3A4 P08684 3/20 0.54
TSHR P16473 2/20 0.54
PARP1 P09874 2/20 0.53
BCHE P06276 2/20 0.48
CES1 P23141 2/20 0.48
CES2 O00748 1/20 0.48
MCL1 Q07820 1/20 0.48
LMNA P02545 1/20 0.44
PABPC1 P11940 3/20 0.42
DNMT1 P26358 2/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29383750 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDTYMSHSD17B10
SCHEMBL571203 0.92 ALDH1A1 (0.85) ALDH1A1KDM4EHPGDTYMSHSD17B10
SCHEMBL27801274 0.88 ALDH1A1 (0.78) ALDH1A1KDM4EHPGDTYMSHSD17B10
SCHEMBL254908 0.84 ALDH1A1 (0.72) ALDH1A1KDM4EHPGDTYMSHSD17B10
SCHEMBL28363174 0.82 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDTYMSHSD17B10
SCHEMBL30067536 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDTYMSHSD17B10
SCHEMBL254933 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDTYMSHSD17B10
SCHEMBL7891792 0.79 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDTYMSHSD17B10
O-Xylene SCHEMBL28132427 0.79 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDTYMSHSD17B10
SCHEMBL30067485 0.77 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDTYMSHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025233-A Bisphenol compound, synthetic method and polycarbonate prepared from bisphenol compound 辽宁科技学院 2025-05-23 CN claimed
CN-116462715-B Acenaphthylene alpha-diimine nickel complex, catalyst and application thereof 中国神华煤制油化工有限公司 2025-05-09 CN claimed
CN-118994262-A Sandwich type asymmetric nickel complex and preparation method and application thereof 山西大学 2024-11-22 CN claimed
CN-117624254-A Preparation method of trimethoxy-containing asymmetric alpha-diimine nickel complex 桂林理工大学 2024-03-01 CN claimed
CN-117486907-A N 2 O-type BODIPY derivative and preparation method and application thereof 安徽师范大学 2024-02-02 CN claimed
CN-116462715-A Acenaphthylene alpha-diimine nickel complex, catalyst and application thereof 中国神华煤制油化工有限公司 2023-07-21 CN claimed
CN-116334785-A Method for preparing covalent cross-linked fiber from covalent adaptive network 东华大学 2023-06-27 CN claimed
CN-112175000-B Multidentate coordination alpha-diimine vanadium catalyst and method for catalyzing ethylene polymerization by using same 华东理工大学 2022-11-15 CN claimed
CN-107466322-B Mutant transaminases and methods and uses related thereto 豪夫迈·罗氏有限公司 2022-04-15 CN claimed
CN-113960220-B Synchronous detection method and application of polycyclic aromatic hydrocarbon and derivatives thereof in blood 生态环境部华南环境科学研究所 2022-03-04 CN claimed
EP-1036076-B1 NOVEL COMPOUNDS ASTRAZENECA UK LTD (GB) 2002-09-04 EP claimed
US-20020099055-A1 Novel compounds ASTRAZENECA AB. 2002-07-25 US claimed
EP-1036076-A1 NOVEL COMPOUNDS AstraZeneca UK Limited (GB) 2000-09-20 EP claimed
WO-1999029695-A1 NOVEL COMPOUNDS ASTRAZENECA UK LIMITED (GB) 1999-06-17 WO claimed
EP-0623127-B1 NOVEL NEUROTRANSMITTER RELEASERS USEFUL FOR COGNITION ENHANCEMENT DU PONT MERCK PHARMA (US) 1997-04-02 EP claimed
EP-0275524-B1 PROCESS FOR THE PREPARATION OF THIOPHENES FROM ALPHA-METHYL KETONES BY THE ONE-POT METHOD, AND ANELLATED THIOPHENES PREPARED BY MEANS OF THIS PROCESS Von der Haar-Czogalla, Rita (DE) 1991-05-15 EP claimed
EP-0136847-B1 PHOTOGRAPHICALLY USEFUL CHALCOGENAZOLYLIDENE AND CHALCOGENAZOLIUM DYES AND METHODS FOR THEIR PREPARATION EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-01-17 EP claimed
US-4876361-A BROMINATION, SULFURIZATION, CYCLIZATION von der Haar-Czogalla, Rita (DE) 1989-10-24 US claimed
EP-0275524-A1 Process for the preparation of thiophenes from alpha-methyl ketones by the one-pot method, and anellated thiophenes prepared by means of this process Von der Haar-Czogalla, Rita (DE) 1988-07-27 EP claimed
EP-0136847-A2 Photographically useful chalcogenazolylidene and chalcogenazolium dyes and methods for their preparation EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020099055-A1 Novel compounds THPO, CYP4B1, CYP3A4 ALDH1A1 2122/4885KDM4E 1121/4885HPGD 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.