Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.50 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712709 | 1.00 | PTGS1 (0.52) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9361691 | 1.00 | PTGS1 (0.52) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9361696 | 1.00 | PTGS1 (0.52) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9200234 | 1.00 | PTGS1 (0.52) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9200236 | 1.00 | PTGS1 (0.52) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL10635746 | 1.00 | PTGS1 (0.52) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9361767 | 0.94 | PTGS1 (0.53) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9623560 | 0.94 | PTGS1 (0.53) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9361761 | 0.94 | PTGS1 (0.53) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9623563 | 0.94 | PTGS1 (0.53) | PTGS1ABCB11PDE4DNR1I2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325923-B1 | CEPHEM COMPOUNDS AND ESBL-DETECTING REAGENTS CONTAINING THE SAME | ZENYAKU KOGYO KK (JP) | 2006-12-06 | — | — | EP | disclosed |
| US-6897304-B2 | Cephem compounds and ESBL-detecting reagents containing the same | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2005-05-24 | — | — | US | disclosed |
| US-20040019202-A1 | Cephem compounds and esbl-detecting reagents containing the same | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-01-29 | — | — | US | disclosed |
| EP-1325923-A1 | CEPHEM COMPOUNDS AND ESBL-DETECTING REAGENTS CONTAINING THE SAME | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-0238060-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4814328-A | Cephalosporin derivatives, and antibacterial agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4782155-A | ISOQUINOLINE SALTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0238060-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019202-A1 | Cephem compounds and esbl-detecting reagents containing the same | MRPL21, CLIC1, QSOX1 | PTGS1 2523/4885ABCB11 282/4885PDE4D 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.