Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 16/20 | 0.40 |
| ▸ | DPP4 | P27487 | 8/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291287 | 1.00 | ITGB3 (0.41) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6766755 | 0.99 | ITGB3 (0.40) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL5713143 | 0.99 | ITGB3 (0.42) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6766760 | 0.99 | ITGB3 (0.40) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL5713147 | 0.99 | ITGB3 (0.42) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6773029 | 0.97 | ITGB3 (0.42) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6773033 | 0.97 | ITGB3 (0.42) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL7288938 | 0.97 | ITGB3 (0.41) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL7288946 | 0.97 | ITGB3 (0.41) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6766608 | 0.96 | ITGB3 (0.40) | ITGB3ITGA2BDPP7DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-B1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | SERVIER LAB (FR) | 2006-01-18 | — | — | EP | disclosed |
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |