Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 14/20 | 0.39 |
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713143 | 1.00 | ITGB3 (0.42) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6773033 | 0.99 | ITGB3 (0.42) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6773029 | 0.99 | ITGB3 (0.42) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL7291287 | 0.99 | ITGB3 (0.41) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL5713136 | 0.99 | ITGB3 (0.41) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6766755 | 0.97 | ITGB3 (0.40) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6766760 | 0.97 | ITGB3 (0.40) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL5713139 | 0.96 | ITGB3 (0.44) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL5713144 | 0.96 | ITGB3 (0.44) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL7288946 | 0.96 | ITGB3 (0.41) | ITGB3ITGA2BDPP7DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-B1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | SERVIER LAB (FR) | 2006-01-18 | — | — | EP | claimed |
| US-6716843-B2 | INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV | LES LABORATOIRES SERVIER (FR) | 2004-04-06 | — | — | US | claimed |
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | LES LABORATOIRES SERVIER (FR) | 2003-05-08 | — | — | US | claimed |
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | claimed |
| EP-1245568-B1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | SERVIER LAB (FR) | 2006-01-18 | — | — | EP | disclosed |
| US-6716843-B2 | INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV | LES LABORATOIRES SERVIER (FR) | 2004-04-06 | — | — | US | disclosed |
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | LES LABORATOIRES SERVIER (FR) | 2003-05-08 | — | — | US | disclosed |
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | DNPEP, DPP4, DPP7 | ITGB3 2050/4885ITGA2B 1751/4885DPP7 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.