Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713156 | 1.00 | DPP4 (0.55) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL6763856 | 0.99 | DPP4 (0.54) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL6763850 | 0.99 | DPP4 (0.54) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL5713163 | 0.97 | DPP4 (0.56) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL5713161 | 0.97 | DPP4 (0.56) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL6768429 | 0.96 | DPP4 (0.55) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL6768433 | 0.96 | DPP4 (0.55) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL5713147 | 0.86 | ITGB3 (0.42) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5713143 | 0.86 | ITGB3 (0.42) | DPP4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6773029 | 0.85 | ITGB3 (0.42) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-B1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | SERVIER LAB (FR) | 2006-01-18 | — | — | EP | disclosed |
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |