Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3313595 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2RAB9AKMT2A | |
| SCHEMBL17894512 | 0.74 | MEN1 (0.43) | ALDH1A1KDM4ESMN1; SMN2FLT1KDR | |
| SCHEMBL18050876 | 0.74 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAOB | |
| SCHEMBL7991370 | 0.74 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAOB | |
| SCHEMBL10558615 | 0.73 | HSP90AA1 (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1OPRD1 | |
| SCHEMBL28261189 | 0.72 | KCNH2 (0.44) | ALDH1A1KDM4ESMN1; SMN2KDRALOX15B | |
| SCHEMBL14476616 | 0.72 | MAOB (0.45) | ALDH1A1KDM4ESMN1; SMN2MAOB | |
| SCHEMBL14476615 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2MAOBCCR1 | |
| SCHEMBL22262823 | 0.72 | KLKB1 (0.51) | KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4314338 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2RAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732901-A1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | Bayer HealthCare AG (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092865-A1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | BAYER HEALTHCARE AG (DE) | 2005-10-06 | — | — | WO | disclosed |