Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991370 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2PKMGAA | |
| SCHEMBL18050897 | 0.85 | PKM (0.49) | SMN1; SMN2PKMGAATSHRSCD | |
| SCHEMBL18050890 | 0.83 | SCD (0.56) | SMN1; SMN2PKMGAATSHRSCD | |
| SCHEMBL11484432 | 0.82 | PKM (0.69) | KDM4EALDH1A1SMN1; SMN2PKMGAA | |
| SCHEMBL18050874 | 0.82 | SCD (0.49) | ALDH1A1SMN1; SMN2PKMGAATSHR | |
| SCHEMBL7984668 | 0.80 | POLB (0.49) | KDM4EALDH1A1SMN1; SMN2NR3C1HIF1A | |
| SCHEMBL2145227 | 0.78 | ADORA3 (0.51) | KDM4EALDH1A1SMN1; SMN2KMT2ANR3C1 | |
| SCHEMBL18050879 | 0.78 | NPC1 (0.47) | ALDH1A1PKMGAATSHRSCD | |
| SCHEMBL18050896 | 0.78 | PKM (0.46) | SMN1; SMN2PKMGAATSHRSCD | |
| SCHEMBL20591092 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106692138-B | Application of N-benzyl imidazole amide derivative as polymyxin antibiotic synergist | 广州英赛特生物技术有限公司 | 2020-08-04 | — | — | CN | disclosed |
| US-10435376-B2 | Derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs | Guangzhou Insighter Biotechnology Co., Ltd. (CN) | 2019-10-08 | — | — | US | disclosed |
| US-10435376-B2 | Derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs | Guangzhou Insighter Biotechnology Co., Ltd. (CN) | 2019-10-08 | — | — | US | disclosed |
| US-20180370921-A1 | Derivatives of 1H-imidazole-4,5-dicarboxamide and Use Thereof in Preparation of Anticoccidial Drugs | GUANGZHOU INSIGHTER BIOTECHNOLOGY CO.,LTD. (CN) | 2018-12-27 | — | — | US | disclosed |
| WO-2017113525-A1 | APPLICATION OF N-BENZYLIMIDAZOLECARBOXAMIDE DERIVATIVES AS SYNERGIST FOR POLYMYXIN ANTIBIOTICS | 广州英赛特生物技术有限公司 | 2017-07-06 | — | — | WO | disclosed |
| WO-2016141736-A1 | GLYCALPYRAMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF ANTICOCCIDIAL DRUG | 广州英赛特生物技术有限公司 | 2016-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180370921-A1 | Derivatives of 1H-imidazole-4,5-dicarboxamide and Use Thereof in Preparation of Anticoccidial Drugs | CYP3A5, DDC, CPS1 | KDM4E 63/4885ALDH1A1 450/4885SMN1; SMN2 4571/4885 |
| US-10435376-B2 | Derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs | CYP3A5, DDC, CPS1 | KDM4E 63/4885ALDH1A1 450/4885SMN1; SMN2 4571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.