Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669334 | 0.87 | TSHR (0.71) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL578128 | 0.87 | TSHR (0.77) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL7670783 | 0.84 | TSHR (0.71) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL14627086 | 0.83 | TSHR (0.56) | TSHRALDH1A1HSD17B10CDC25BKMT2A | |
| SCHEMBL11590516 | 0.83 | TSHR (0.61) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| Diethyl Phthalate SCHEMBL22296 | 0.82 | TSHR (1.00) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| Diethyl Phthalate SCHEMBL5306972 | 0.82 | TSHR (1.00) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| Diethyl Phthalate SCHEMBL29404255 | 0.82 | TSHR (1.00) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL11591314 | 0.82 | TSHR (0.59) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL11061326 | 0.82 | TSHR (0.69) | TSHRALDH1A1HSD17B10CDC25BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368381-B1 | 2-ALKYLATED-CYCLODEXTRIN DERIVATIVES: REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | AKZO NOBEL NV (NL) | 2006-05-03 | — | — | EP | disclosed |
| US-7026304-B2 | 2-alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block | AKZO NOBEL N.V. (NL) | 2006-04-11 | — | — | US | disclosed |
| US-20040106575-A1 | 2-Alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block | MERCK SHARP & DOHME B.V. (NL) | 2004-06-03 | — | — | US | disclosed |
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1368381-A1 | 2-ALKYLATED-CYCLODEXTRIN DERIVATIVES: REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | Akzo Nobel N.V. (NL) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002064635-A1 | 2-ALKYLATED-CYCLODEXTRIN DERIVATIVES: REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | AKZO NOBEL N.V. (NL) | 2002-08-22 | — | — | WO | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| CN-1209809-A | Noval chemical compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-03-03 | — | — | CN | disclosed |
| EP-0880519-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027190-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106575-A1 | 2-Alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block | SCN1B, SCN2B, CHRNB1 | TSHR 3020/4885ALDH1A1 3591/4885HSD17B10 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.