SCHEMBL5713430

SCHEMBL5713430

c1ccc2cc3c(-c4c5ccccc5c(-c5cccc6cc7ccccc7cc56)c5ccccc45)cccc3cc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.48
ALDH1A1 P00352 8/20 0.47
HSD17B10 Q99714 6/20 0.47
HPGD P15428 4/20 0.47
HIF1A Q16665 3/20 0.47
TSHR P16473 3/20 0.47
MAPK1 P28482 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
CASP1 P29466 2/20 0.47
CYP1B1 Q16678 1/20 0.46
SOS1 Q07889 1/20 0.45
TP53 P04637 1/20 0.43
CASP7 P55210 1/20 0.43
KDM4E B2RXH2 3/20 0.42
GAA P10253 2/20 0.42
CYP1A2 P05177 3/20 0.42
ERBB2 P04626 1/20 0.42
FYN P06241 1/20 0.42
MAOA P21397 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28576924 0.95 CES1 (0.53) CES1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL8361231 0.90 ALDH1A1 (0.52) CES1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL6242477 0.86 ALDH1A1 (0.48) CES1ALDH1A1HSD17B10HPGDHIF1A
Hydrazine SCHEMBL2329114 0.86 ALDH1A1 (0.48) CES1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL28129642 0.86 ESR1 (0.56) CES1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL29354014 0.85 ALDH1A1 (0.50) CES1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL2871930 0.85 ALDH1A1 (0.50) CES1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL2551156 0.85 ALDH1A1 (0.52) CES1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL29593313 0.84 ALDH1A1 (0.54) CES1ALDH1A1HSD17B10HPGDHIF1A
SCHEMBL440879 0.84 ALDH1A1 (0.54) CES1ALDH1A1HSD17B10HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221473-B1 Organic light emitting diode device with three component emitting layer EASTMAN KODAK CO (US) 2006-09-06 EP disclosed
US-6720090-B2 ELECTROLUMINESCENT (EL) DEVICES EASTMAN KODAK COMPANY 2004-04-13 US disclosed
US-20020127427-A1 Organic light emitting diode devices with improved luminance efficiency EASTMAN KODAK COMPANY 2002-09-12 US disclosed
EP-1221473-A1 Organic light emitting diode device with three component emitting layer EASTMAN KODAK COMPANY (US) 2002-07-10 EP disclosed