Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.52 |
| ▸ | ARG1 | P05089 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713517 | 0.83 | TUBB4A (0.58) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5713616 | 0.82 | ARG1 (0.70) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5713600 | 0.82 | FFAR1 (0.52) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5713621 | 0.80 | MAPT (0.71) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8234606 | 0.80 | HTT (0.62) | MAPTMEN1KMT2AMAOBNPC1 | |
| SCHEMBL5713700 | 0.79 | LRRK2 (0.49) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6700054 | 0.79 | CHRM2 (0.55) | MAPTEGFRMEN1KMT2AMAOB | |
| SCHEMBL632217 | 0.79 | CHRM2 (0.55) | MAPTEGFRMEN1KMT2AMAOB | |
| SCHEMBL5713561 | 0.78 | ARG1 (0.54) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11510712 | 0.77 | HDAC4 (0.54) | MEN1KMT2AMAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251822-A4 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P & G CLAIROL INC (US) | 2006-05-31 | — | — | EP | disclosed |
| CN-1196464-C | Novel couplers for oxidative hair dyeing | P & G CLAROR INC (US) | 2005-04-13 | — | — | CN | disclosed |
| US-6540793-B1 | Coupler for use in oxidative hair dyeing | CLAIROL INCORPORATED | 2003-04-01 | — | — | US | disclosed |
| CN-1396819-A | Novel couplers for oxidative hair dyeing | P & G CLAROR INC (US) | 2003-02-12 | — | — | CN | disclosed |
| EP-1251822-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | Clairol Incorporated (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001056538-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2001-08-09 | — | — | WO | disclosed |