Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 11/20 | 0.45 |
| ▸ | GSTM2 | P28161 | 11/20 | 0.45 |
| ▸ | MYC | P01106 | 4/20 | 0.45 |
| ▸ | MAX | P61244 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5714466 | 0.99 | GSTP1 (0.47) | GSTP1GSTM2MYCMAXMEN1 | |
| SCHEMBL5714474 | 0.99 | GSTP1 (0.47) | GSTP1GSTM2MYCMAXMEN1 | |
| SCHEMBL5713929 | 0.88 | GSTP1 (0.46) | GSTP1GSTM2MYCMAXMEN1 | |
| SCHEMBL5714469 | 0.88 | GSTP1 (0.44) | GSTP1GSTM2MYCMAXMEN1 | |
| SCHEMBL5713694 | 0.87 | GSTP1 (0.48) | GSTP1GSTM2MYCMAXIDO1 | |
| SCHEMBL5713701 | 0.87 | GSTP1 (0.48) | GSTP1GSTM2MYCMAXMEN1 | |
| SCHEMBL5714132 | 0.85 | GSTP1 (0.48) | GSTP1GSTM2MYCMAXMEN1 | |
| SCHEMBL5713930 | 0.84 | GSTP1 (0.47) | GSTP1GSTM2MYCMAXMEN1 | |
| SCHEMBL5713654 | 0.84 | GSTM2 (0.49) | GSTP1GSTM2MEN1KMT2AIDO1 | |
| SCHEMBL5713923 | 0.84 | GSTP1 (0.50) | GSTP1GSTM2MYCMAXMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261591-B1 | 7-NITRO-2,1,3-BENZOXADIAZOLE DERIVATIVES AND 7-NITRO-2,1,3-BENZTHIADIAZOLE DERIVATIVES AND DYES, WHICH CONTAIN THESE COMPOUNDS AND WHICH ARE USED FOR DYING KERATIN FIBERS | WELLA AG (DE) | 2006-03-08 | — | — | EP | claimed |
| US-20040139563-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-07-22 | — | — | US | claimed |
| US-20040139562-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-07-22 | — | — | US | claimed |
| US-20030171594-A1 | 7-Nitro-2,1,3-benzoxadiazole derivatives and 7-nitro-2,1,3-benzthiadiazole derivatives and dyes, which contain these compounds and which are used for dying keratin fibers | Wella GmbH (DE) | 2003-09-11 | — | — | US | claimed |
| EP-1261591-A1 | 7-NITRO-2,1,3-BENZOXADIAZOLE DERIVATIVES AND 7-NITRO-2,1,3-BENZTHIADIAZOLE DERIVATIVES AND DYES, WHICH CONTAIN THESE COMPOUNDS AND WHICH ARE USED FOR DYING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2002-12-04 | — | — | EP | claimed |
| WO-2002076961-A1 | 7-NITRO-2,1,3-BENZOXADIAZOLE DERIVATIVES AND 7-NITRO-2,1,3-BENZTHIADIAZOLE DERIVATIVES AND DYES, WHICH CONTAIN THESE COMPOUNDS AND WHICH ARE USED FOR DYING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | WO | claimed |
| US-7083656-B2 | 7-nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | WELLA AG (DE) | 2006-08-01 | — | — | US | disclosed |
| US-6908492-B2 | 7-nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-06-21 | — | — | US | disclosed |
| US-6869454-B2 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-03-22 | — | — | US | disclosed |
| US-20040226108-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-11-18 | — | — | US | disclosed |
| US-20040139563-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-07-22 | — | — | US | disclosed |
| US-20040139562-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-07-22 | — | — | US | disclosed |
| US-6726730-B2 | HAIR DYES WHICH ARE READILY SOLUBLE IN WATER AND DISTINGUISHED BY UNIFORM ABSORPTION BEHAVIOR AND HIGH WASHING STABILITY; ENABLE DYEING UNDER GENTLE AND SKIN-COMPATIBLE CONDITIONS | WELLA AKTIENGESELLSCHAFT (DE) | 2004-04-27 | — | — | US | disclosed |
| US-20030171594-A1 | 7-Nitro-2,1,3-benzoxadiazole derivatives and 7-nitro-2,1,3-benzthiadiazole derivatives and dyes, which contain these compounds and which are used for dying keratin fibers | Wella GmbH (DE) | 2003-09-11 | — | — | US | disclosed |
| EP-1261591-A1 | 7-NITRO-2,1,3-BENZOXADIAZOLE DERIVATIVES AND 7-NITRO-2,1,3-BENZTHIADIAZOLE DERIVATIVES AND DYES, WHICH CONTAIN THESE COMPOUNDS AND WHICH ARE USED FOR DYING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2002-12-04 | — | — | EP | disclosed |
| WO-2002076961-A1 | 7-NITRO-2,1,3-BENZOXADIAZOLE DERIVATIVES AND 7-NITRO-2,1,3-BENZTHIADIAZOLE DERIVATIVES AND DYES, WHICH CONTAIN THESE COMPOUNDS AND WHICH ARE USED FOR DYING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040226108-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | KRT18, NUCB2, NDUFA3 | GSTP1 3179/4885GSTM2 3009/4885MYC 3346/4885 |
| US-20040139562-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | KRT18, CNN2, TUBB1 | GSTP1 2128/4885GSTM2 2110/4885MYC 3881/4885 |
| US-20030171594-A1 | 7-Nitro-2,1,3-benzoxadiazole derivatives and 7-nitro-2,1,3-benzthiadiazole derivatives and dyes, which contain these compounds and which are used for dying keratin fibers | KRT18, CASP5, CASP7 | GSTP1 2412/4885GSTM2 2464/4885MYC 3769/4885 |
| US-20040139563-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | KRT18, CNN2, TUBB1 | GSTP1 2128/4885GSTM2 2110/4885MYC 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.