Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219611 | 1.00 | SIGMAR1 (0.54) | SIGMAR1CARM1PRMT6PRMT8ATM | |
| SCHEMBL6220586 | 0.95 | SIGMAR1 (0.57) | SIGMAR1CARM1PRMT6PRMT8ATM | |
| SCHEMBL8399769 | 0.83 | SIGMAR1 (0.57) | SIGMAR1CARM1PRMT6PRMT8ATM | |
| SCHEMBL4796764 | 0.83 | SIGMAR1 (0.49) | SIGMAR1CARM1PRMT6PRMT8ATM | |
| SCHEMBL19715797 | 0.80 | SIGMAR1 (0.57) | SIGMAR1CARM1PRMT6PRMT8ATM | |
| SCHEMBL14923120 | 0.80 | DNM1 (0.59) | CARM1PRMT6PRMT8MEN1KMT2A | |
| SCHEMBL14582439 | 0.80 | SIGMAR1 (0.61) | SIGMAR1CARM1PRMT6PRMT8ATM | |
| SCHEMBL5479079 | 0.79 | CARM1 (0.51) | SIGMAR1CARM1PRMT6PRMT8ATM | |
| SCHEMBL4798715 | 0.79 | CARM1 (0.51) | SIGMAR1CARM1PRMT6PRMT8ATM | |
| SCHEMBL1088446 | 0.78 | SIGMAR1 (0.74) | SIGMAR1CARM1PRMT6PRMT8TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725518-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005092835-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-10-06 | — | — | WO | disclosed |