SCHEMBL5715903

SCHEMBL5715903

CCCCC(CC)CCN(C)c1c(F)c(C)c(F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
CA2 P00918 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715798 0.92 ALDH1A1 (0.38) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL5715733 0.87 TAS1R3 (0.34) TAS1R3TAS1R1TAS1R2ALDH1A1TDP1
SCHEMBL5716472 0.84 TAS1R3 (0.34) TAS1R3TAS1R1TAS1R2ALDH1A1TDP1
SCHEMBL5716619 0.82 TAS1R3 (0.33) TAS1R3TAS1R1TAS1R2ALDH1A1TDP1
SCHEMBL5716300 0.81 TAS1R3 (0.32) TAS1R3TAS1R1TAS1R2
SCHEMBL6793044 0.75 ALDH1A1 (0.37) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL6790248 0.75 ALDH1A1 (0.37) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL6792676 0.73 ALDH1A1 (0.35) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL5716374 0.73 ALDH1A1 (0.35) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL5715787 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed