SCHEMBL5715927

SCHEMBL5715927

Fc1cc(N2Cc3ccccc3C2)c(F)c(F)c1F

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPT P10636 6/20 0.41
TAS1R3 Q7RTX0 2/20 0.41
TAS1R1 Q7RTX1 2/20 0.41
TAS1R2 Q8TE23 2/20 0.41
LMNA P02545 2/20 0.40
KMT2A Q03164 5/20 0.38
MEN1 O00255 4/20 0.38
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
GAA P10253 1/20 0.37
TIPARP Q7Z3E1 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NOTUM Q6P988 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715789 0.84 ALDH1A1 (0.44) ALDH1A1HPGDSMN1; SMN2MAPTTAS1R3
SCHEMBL5923940 0.82 ALDH1A1 (0.47) ALDH1A1HPGDSMN1; SMN2MAPTTAS1R3
SCHEMBL5716438 0.82 ALDH1A1 (0.39) ALDH1A1HPGDSMN1; SMN2MAPTTAS1R3
SCHEMBL7611671 0.75 ALDH1A1 (0.57) ALDH1A1HPGDSMN1; SMN2MAPTLMNA
SCHEMBL5716477 0.74 ALDH1A1 (0.52) ALDH1A1HPGDSMN1; SMN2MAPTTAS1R3
SCHEMBL5715513 0.73 ALDH1A1 (0.46) ALDH1A1HPGDSMN1; SMN2MAPTTAS1R3
SCHEMBL5715607 0.73 TAS1R3 (0.50) ALDH1A1HPGDSMN1; SMN2MAPTTAS1R3
SCHEMBL5716317 0.73 ALDH1A1 (0.43) ALDH1A1HPGDSMN1; SMN2MAPTTAS1R3
SCHEMBL6792994 0.72 NPC1 (0.53) SMN1; SMN2MAPTLMNAKMT2AMEN1
SCHEMBL5716185 0.72 ALDH1A1 (0.48) ALDH1A1HPGDSMN1; SMN2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed