SCHEMBL5715951

SCHEMBL5715951

CCCCC(CC)CCNCF.Fc1ccc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
CYP3A4 P08684 2/20 0.34
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.33
EPHX2 P34913 1/20 0.32
LMNA P02545 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715770 0.91 ALDH1A1 (0.35) ALDH1A1CYP3A4TSHRKDM4EEPHX2
SCHEMBL5715913 0.91 ALDH1A1 (0.35) ALDH1A1CYP3A4TSHRKDM4EEPHX2
SCHEMBL6439619 0.90 EPHX2 (0.36) ALDH1A1CYP3A4TSHRKDM4EEPHX2
SCHEMBL5715944 0.89 EPHX2 (0.38) ALDH1A1CYP3A4TSHRKDM4EEPHX2
SCHEMBL5715753 0.83 EPHX2 (0.43) ALDH1A1TSHREPHX2LMNA
SCHEMBL6460674 0.83 ALDH1A1 (0.40) ALDH1A1CYP3A4TSHRKDM4ELMNA
SCHEMBL5716126 0.82 EPHX2 (0.32) EPHX2
SCHEMBL5716005 0.78 EPHX2 (0.38) ALDH1A1TSHREPHX2
SCHEMBL5715701 0.78 ALDH1A1 (0.38) ALDH1A1CYP3A4TSHRKDM4ELMNA
SCHEMBL5716452 0.76 EPHX2 (0.37) ALDH1A1TSHREPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed