Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272984 | 0.93 | RARB (0.50) | RARBRARGRARAEGFR | |
| Isophthalic Acid SCHEMBL9868948 | 0.92 | RARB (0.45) | RARBRARGRARACYP2C9KMO | |
| Terephthalic Acid SCHEMBL11133121 | 0.89 | RARB (0.48) | RARBRARGRARAEGFRNPC1 | |
| SCHEMBL11439076 | 0.87 | RARB (0.50) | RARBRARGRARACTRCACMSD | |
| Terephthalic Acid SCHEMBL8151569 | 0.86 | RARB (0.44) | RARBRARGRARAKMONPC1 | |
| SCHEMBL3263009 | 0.85 | RARB (0.50) | RARBRARGRARA | |
| SCHEMBL36556 | 0.84 | GSTP1 (0.45) | TSHRCYP2C9 | |
| Terephthalic Acid SCHEMBL2463379 | 0.83 | NPC1 (0.46) | DAOTSHRNAPRTCES2CES1 | |
| SCHEMBL2988208 | 0.83 | SOS1 (0.47) | TSHRACMSDCYP2C9RAB9A | |
| Terephthalic Acid SCHEMBL3979457 | 0.82 | TSHR (0.50) | DAOTSHRNAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056573-B2 | Transparent, high-gloss plastic films, e.g. biaxially oriented films; for use in interior decoration, as display, for placards, for protective glazing, in lighting sector, in fitting out of shops or stores, as promotional item | MITSUBISHI POLYESTER FILM GMBH (DE) | 2006-06-06 | — | — | US | disclosed |
| US-6872461-B2 | Matt, flame-retardant, co-extruded polyester film, a method for the production thereof and the use of the same | MITSUBISHI POLYESTER FILM GMBH (DE) | 2005-03-29 | — | — | US | disclosed |
| US-6841222-B2 | To extend the sealing range of the film to low temperatures, to increase the seal seam strength of the film, and at the same time to provide better handling of the film | MITSUBISHI POLYESTER FILM GMBH (DE) | 2005-01-11 | — | — | US | disclosed |
| US-6730406-B2 | A BIAXIAL ORIENTED FILM COMPRISING A BLEND OF A POLYETHYLENE TEREPHTHALATE HOMO- OR COPOLYMER AND A POLYMER CONTAINING AT LEAST AN ALKALI METAL SULPHONATE GROUP ON THE AROMATIC DICARBOXYLIC ACID; NON-EMBRITTLE ON EXPOSURE TO HEAT | MITSUBISHI POLYESTER FILM GMBH (DE) | 2004-05-04 | — | — | US | disclosed |
| US-20030157352-A1 | Transparent, high-gloss plastic films, e.g. biaxially oriented films; for use in interior decoration, as display, for placards, for protective glazing, in lighting sector, in fitting out of shops or stores, as promotional item | MITSUBISHI POLYESTER FILM GMBH (DE) | 2003-08-21 | — | — | US | disclosed |
| US-20030108754-A1 | A biaxial oriented film comprising a blend of a polyethylene terephthalate homo- or copolymer and a polymer containing at least an alkali metal sulphonate group on the aromatic dicarboxylic acid; non-embrittle on exposure to heat | MITSUBISHI POLYESTER FILM GMBH (DE) | 2003-06-12 | — | — | US | disclosed |
| US-20030087105-A1 | Matt, flame-retardant, co-extruded polyester film, a method for the production thereof and the use of the same | MITSUBISHI POLYESTER FILM GMBH (DE) | 2003-05-08 | — | — | US | disclosed |
| US-6551686-B1 | Three layers including polyethylene terephthalate | MITSUBISHI POLYESTER FILM GMBH (DE) | 2003-04-22 | — | — | US | disclosed |
| US-6423401-B2 | MULTILAYER; LOW TEMPERATURE SEALING | MITSUBISHI POLYESTER FILM GMBH (DE) | 2002-07-23 | — | — | US | disclosed |
| US-6376042-B1 | EXTERIOR LAYER CONTAINING PARTICLES; GAS AND OXYGEN BARRIER | MITSUBISHI POLYESTER FILM GMBH (DE) | 2002-04-23 | — | — | US | disclosed |
| US-20010035593-A1 | Multilayer; low temperature sealing | MITSUBISHI POLYESTER FILM GMBH (DE) | 2001-11-01 | — | — | US | disclosed |
| US-6261663-B1 | BLEND WITH PARTICLES | MITSUBISHI POLYSTER FILM GMBH (DE) | 2001-07-17 | — | — | US | disclosed |