Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | BAD | Q92934 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319785 | 0.98 | BCL2L1 (0.50) | TSHRTP53NPC1RAB9ABCL2L1 | |
| Terephthalic Acid SCHEMBL28279901 | 0.96 | TSHR (0.46) | TSHRTP53NPC1RAB9ABCL2L1 | |
| Terephthalic Acid SCHEMBL2463379 | 0.93 | NPC1 (0.46) | TSHRTP53NPC1RAB9ABCL2L1 | |
| Terephthalic Acid SCHEMBL1234263 | 0.92 | TSHR (0.46) | TSHRTP53NPC1RAB9ABCL2L1 | |
| Terephthalic Acid SCHEMBL28622230 | 0.92 | TSHR (0.46) | TSHRTP53NPC1RAB9ABCL2L1 | |
| SCHEMBL8485036 | 0.90 | BCL2L1 (0.47) | TSHRTP53NPC1RAB9ABCL2L1 | |
| Isophthalic Acid SCHEMBL8500503 | 0.89 | KMO (0.49) | BCL2L1BADEGFRCA12CA1 | |
| Terephthalic Acid SCHEMBL9267638 | 0.88 | HDAC3 (0.42) | TSHRTP53NPC1RAB9ABCL2L1 | |
| SCHEMBL3263009 | 0.87 | RARB (0.50) | TP53HPGD | |
| Terephthalic Acid SCHEMBL10383269 | 0.87 | TSHR (0.41) | TSHRTP53NPC1RAB9ABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-210627248-U | Thing networking retail tracking uses antifalsification label | 苏州菱慧电子科技有限公司 | 2020-05-26 | — | — | CN | claimed |
| CN-210402430-U | Thing networking material is tracked with anti-fake anti-tear label | 苏州菱慧电子科技有限公司 | 2020-04-24 | — | — | CN | claimed |
| CN-110826678-A | Thing networking retail tracking uses antifalsification label | 苏州菱慧电子科技有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110705677-A | Thing networking material is tracked with anti-fake anti-tear label | 苏州菱慧电子科技有限公司 | 2020-01-17 | — | — | CN | claimed |
| US-8951225-B2 | Catheters with non-removable guide members useable for treatment of sinusitis | ACCLARENT, INC. (US) | 2015-02-10 | — | — | US | claimed |
| EP-2024001-A2 | CATHETERS WITH NON-REMOVABLE GUIDE MEMBERS USEABLE FOR TREATMENT OF SINUSITIS | Acclarent, Inc. (US) | 2009-02-18 | — | — | EP | claimed |
| WO-2007136584-A2 | CATHETERS WITH NON-REMOVABLE GUIDE MEMBERS USEABLE FOR TREATMENT OF SINUSITIS | ACCLARENT, INC. (US) | 2007-11-29 | — | — | WO | claimed |
| US-20070208301-A1 | Catheters with non-removable guide members useable for treatment of sinusitis | ACCLARENT, INC. (US) | 2007-09-06 | — | — | US | claimed |
| CN-110300610-A | INHALER DEVICE FOR INHALABLE LIQUIDS | 医疗发展国际有限公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-109791966-A | Light emitting device package | LG 伊诺特有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109429532-A | Light emitting device package and light source equipment | LG 伊诺特有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-108633317-A | Light emitting device package and lighting apparatus including the light emitting device package | LG 伊诺特有限公司 | 2018-10-09 | — | — | CN | disclosed |