SCHEMBL5716469

SCHEMBL5716469

CCCCCCN(CCCC)c1cc(F)c(F)c(C(F)(F)F)c1F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
AR P10275 2/20 0.33
ALPL P05186 1/20 0.31
ALPI P09923 1/20 0.31
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715888 0.98 CYP3A4 (0.33) CYP3A4MAPTMAPK1AR
SCHEMBL5715588 0.96 CYP3A4 (0.32) CYP3A4MAPTMAPK1
SCHEMBL5716134 0.93 CYP3A4 (0.36) CYP3A4MAPTMAPK1
SCHEMBL5716392 0.93 CYP3A4 (0.35) CYP3A4MAPTMAPK1ARALPL
SCHEMBL6787541 0.92 CYP3A4 (0.31) CYP3A4MAPTMAPK1
SCHEMBL5715818 0.87
SCHEMBL5716236 0.86 DNM1 (0.33) CYP3A4MAPTMAPK1
SCHEMBL5716198 0.85
SCHEMBL5715870 0.85
SCHEMBL5715850 0.84 DNM1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed