SCHEMBL5716236

SCHEMBL5716236

CCCCCCCCCN(CCCC)c1cc(F)c(F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.33
EPHX2 P34913 1/20 0.31
GPR84 Q9NQS5 2/20 0.30
CRHR1 P34998 2/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715850 0.98 DNM1 (0.34) DNM1EPHX2GPR84
SCHEMBL5716558 0.98 DNM1 (0.34) DNM1EPHX2GPR84
SCHEMBL5715816 0.92 KDM4E (0.34) DNM1EPHX2CRHR1CYP3A4MAPT
SCHEMBL5716183 0.90 DNM1 (0.31) DNM1
SCHEMBL5716469 0.86 CYP3A4 (0.35) CYP3A4MAPTMAPK1
SCHEMBL5715888 0.84 CYP3A4 (0.33) CYP3A4MAPTMAPK1
SCHEMBL6792443 0.83 ALDH3A1 (0.35) CYP3A4MAPK1
SCHEMBL5716169 0.83 GPR84 (0.40) DNM1EPHX2GPR84
SCHEMBL5715707 0.82
SCHEMBL5715588 0.82 CYP3A4 (0.32) CYP3A4MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed