Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19358328 | 0.98 | PTPN11 (0.56) | PTPN11RARBNR5A1PTPN1PLA2G2A | |
| SCHEMBL10090891 | 0.92 | PTPN11 (0.52) | PTPN11RARBNR5A1PTPN1 | |
| SCHEMBL31425691 | 0.92 | PTPN11 (0.52) | PTPN11RARBNR5A1PTPN1 | |
| SCHEMBL5550301 | 0.92 | PTPN11 (0.52) | PTPN11RARBNR5A1PTPN1 | |
| SCHEMBL1630438 | 0.92 | PTPN11 (0.52) | PTPN11RARBNR5A1PTPN1 | |
| SCHEMBL10090875 | 0.92 | PTPN11 (0.52) | PTPN11RARBNR5A1PTPN1 | |
| SCHEMBL9635563 | 0.91 | PTPN11 (0.54) | PTPN11RARBNR5A1PTPN1PLA2G2A | |
| SCHEMBL6017413 | 0.89 | PTPN11 (0.51) | PTPN11RARBNR5A1IDH1CYP1A2 | |
| SCHEMBL1468260 | 0.89 | PTPN11 (0.54) | PTPN11RARBNR5A1PTPN1 | |
| SCHEMBL7887565 | 0.89 | PTPN11 (0.54) | PTPN11RARBNR5A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627011-A2 | HIGHLY COMPATIBLE AND NON-MIGRATORY POLYMERIC UV-ABSORBER | Ciba SC Holding AG (CH) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004104081-A2 | HIGHLY COMPATIBLE AND NON-MIGRATORY POLYMERIC UV-ABSORBER | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-12-02 | — | — | WO | disclosed |