Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.54 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635572 | 0.96 | IDH1 (0.51) | PTPN11IDH1MEN1NTSR1KMT2A | |
| SCHEMBL19358328 | 0.93 | PTPN11 (0.56) | PTPN11NR5A1PTPN1DHODHPDK2 | |
| SCHEMBL5716522 | 0.91 | PTPN11 (0.54) | PTPN11IDH1NR5A1PTPN1DHODH | |
| SCHEMBL38951 | 0.89 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL7887565 | 0.89 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL7125656 | 0.89 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL9858733 | 0.89 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL4215764 | 0.89 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL1467411 | 0.89 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL1468260 | 0.89 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280654-B1 | PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS | CIBA-GEIGY AG (CH) | 1992-05-13 | — | — | EP | disclosed |
| US-4895981-A | Using ultraviolet absorber | CIBA-GEIGY CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |