Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715863 | 0.90 | EPHX2 (0.33) | CTSLCTSSCTSK | |
| Methylethylamine SCHEMBL5716369 | 0.89 | TRPV3 (0.32) | CTSLCTSSCTSKTRPV3 | |
| SCHEMBL5716271 | 0.87 | TSHR (0.44) | CTSLCTSSCTSK | |
| SCHEMBL29967714 | 0.83 | CES2 (0.37) | CTSLCTSSCTSK | |
| SCHEMBL1868825 | 0.83 | CES2 (0.37) | CTSLCTSSCTSK | |
| Boric Acid SCHEMBL6799213 | 0.83 | EPHX2 (0.32) | — | |
| SCHEMBL5716005 | 0.82 | EPHX2 (0.38) | CTSLCTSSCTSK | |
| SCHEMBL5716126 | 0.81 | EPHX2 (0.32) | CTSLCTSSCTSK | |
| SCHEMBL7924229 | 0.81 | CES2 (0.36) | CTSLCTSSCTSK | |
| Water SCHEMBL5503134 | 0.81 | CES2 (0.36) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661900-A1 | Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them | ExxonMobil Chemical Patents Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1252166-B1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1252166-A1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXON CHEMICAL PATENTS INC. (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001042249-A1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM | EXXON CHEMICAL PATENTS INC. (US) | 2001-06-14 | — | — | WO | disclosed |