SCHEMBL5716614

SCHEMBL5716614

Cc1c(F)c(F)c(F)c(NC(F)F)c1F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.31
TAS1R1 Q7RTX1 2/20 0.31
TAS1R2 Q8TE23 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6799170 0.84 CA1 (0.32)
SCHEMBL18593300 0.70 CA1 (0.43)
SCHEMBL107094 0.69 TAS1R3 (0.33) TAS1R3TAS1R1TAS1R2
SCHEMBL12256409 0.66 TAS1R3 (0.32) TAS1R3TAS1R1TAS1R2
SCHEMBL6284346 0.66 KDM4E (0.40)
SCHEMBL5510192 0.66 TAS1R3 (0.31) TAS1R3TAS1R1TAS1R2
SCHEMBL926802 0.66 TAS1R3 (0.35) TAS1R3TAS1R1TAS1R2
SCHEMBL16451266 0.64 MEN1 (0.40) TAS1R3TAS1R1TAS1R2
SCHEMBL4343529 0.64 CA12 (0.46) TAS1R3TAS1R1TAS1R2
Bromide SCHEMBL9813316 0.62 TAS1R3 (0.33) TAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed