Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20223494 | 0.84 | KDM4E (0.36) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL15425917 | 0.80 | MAPT (0.34) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL22905127 | 0.78 | KMT2A (0.43) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL21571877 | 0.78 | SMN1; SMN2 (0.36) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL15425916 | 0.78 | F2 (0.36) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL17091729 | 0.75 | CA1 (0.59) | CA1CA2 | |
| SCHEMBL6799170 | 0.71 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL20149220 | 0.70 | KDM4E (0.32) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL12273863 | 0.67 | RAPGEF4 (0.43) | MAPTKMT2ATDP1 | |
| SCHEMBL7135547 | 0.67 | TDP1 (0.42) | KDM4EMEN1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-01-16 | — | — | US | disclosed |
| CN-1284626-C | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | EXXONMOBIL CHEM PATENTS INC (US) | 2006-11-15 | — | — | CN | disclosed |
| US-6919291-B2 | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040110631-A1 | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-06-10 | — | — | US | disclosed |
| CN-1477995-A | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | 埃克森美孚化学专利公司 | 2004-02-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | AHR, DDT, AOC2 | KDM4E 1487/4885MEN1 2686/4885NPC1 2304/4885 |
| US-20040110631-A1 | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | FZD7, FOS, COG4 | KDM4E 4487/4885MEN1 1928/4885NPC1 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.