Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5716646 | 0.89 | KCNA3 (0.40) | KCNA3POLBHCRTR1NPC1RAB9A | |
| SCHEMBL3377865 | 0.86 | POLB (0.48) | KCNA3POLBNPC1RAB9AKDM4E | |
| SCHEMBL3377283 | 0.80 | HCRTR1 (0.45) | POLBHCRTR1KDM4EPTPN1HPGD | |
| SCHEMBL3375839 | 0.80 | ALDH1A1 (0.45) | HCRTR1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL3377828 | 0.79 | MEN1 (0.51) | RAB9AKDM4EHPGDALDH1A1MAPK1 | |
| SCHEMBL5716651 | 0.79 | RAB9A (0.38) | KCNA3POLBNPC1RAB9AKDM4E | |
| SCHEMBL5716638 | 0.79 | NPC1 (0.49) | NPC1RAB9AKDM4ETAAR1HPGD | |
| SCHEMBL5716637 | 0.79 | NPC1 (0.38) | KCNA3POLBNPC1RAB9AKDM4E | |
| SCHEMBL551925 | 0.79 | ALDH1A1 (0.42) | POLBKDM4EMRGPRX1HPGDALDH1A1 | |
| SCHEMBL3376166 | 0.78 | TSHR (0.54) | HCRTR1KDM4EPTPN1HPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727804-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005095351-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |