SCHEMBL5716668

SCHEMBL5716668

[CH2]c1ccccc1O[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA12 O43570 1/20 0.36
CA4 P22748 1/20 0.36
CA14 Q9ULX7 1/20 0.36
TSHR P16473 2/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TP53 P04637 1/20 0.30
ALDH1A1 P00352 1/20 0.30
ADRA2B P18089 1/20 0.30
PTGS1 P23219 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6703730 0.82 CA1 (0.45) CA1CA2CA7CA9CA12
SCHEMBL9117232 0.79 CA12 (0.33) CA1CA2CA7CA9CA12
SCHEMBL18925853 0.75 ALDH1A1 (0.39) CA1CA2CA7CA9CA12
SCHEMBL10913475 0.73 TSHR (0.50) CA1CA2CA7CA9CA12
SCHEMBL27932248 0.73 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL31036946 0.73 TSHR (0.50) CA1CA2CA7CA9CA12
SCHEMBL27825193 0.72
SCHEMBL7 0.72
SCHEMBL8464066 0.71 LMNA (0.42) CA1CA2CA7CA9CA12
SCHEMBL9196056 0.71 ALDH1A1 (0.56) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63090534-A None JP disclosed
EP-1123321-B1 SUPPORTED BIDENTATE AND TRIDENTATE CATALYST COMPOSITIONS AND OLEFIN POLYMERIZATION USING SAME GRACE W R & CO (US) 2006-12-20 EP disclosed
US-7108955-B2 Polysiloxane, process for production thereof and radiation-sensitive resin composition JSR CORPORATION (JP) 2006-09-19 US disclosed
CN-1249126-C Polysiloxane, process for production thereof and radiation-sensitive resin composition JSR CORP (JP) 2006-04-05 CN disclosed
US-6846895-B2 Polysiloxane, method of manufacturing same, silicon-containing alicyclic compound, and radiation-sensitive resin composition JSR CORPORATION (JP) 2005-01-25 US disclosed
US-20040143082-A1 Polysiloxane, process for production thereof and radiation-sensitive resin composition JSR CORPORATION (JP) 2004-07-22 US disclosed
CN-1505651-A Polysiloxane, process for production thereof and radiation-sensitive resin composition JSR��ʽ���� 2004-06-16 CN disclosed
CN-1146583-C Supported bidentate and tridentate catalyst compositions and olefin polymerization using same 2004-04-21 CN disclosed
EP-1398339-A1 POLYSILOXANE, PROCESS FOR PRODUCTION THEREOF AND RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2004-03-17 EP disclosed
EP-1142928-B1 Polysiloxane, method of manufacturing same, silicon-containing alicyclic compound, and radiation-sensitive resin compounds JSR CORP (JP) 2004-02-18 EP disclosed
US-6531260-B2 Photoresist JSR CORPORATION (JP) 2003-03-11 US disclosed
CN-1328576-A Supported bidentate and tridentate catalyst compositions and olefin polymerization using same GRACE W R & CO (US) 2001-12-26 CN disclosed
US-20010041769-A1 Polysiloxane, method of manufacturing same, silicon-containingalicyclic compouns, and radiation-sensitive resin composition JSR CORPORATION (JP) 2001-11-15 US disclosed
EP-1142928-A1 Polysiloxane, method of manufacturing same, silicon-containing alicyclic compound, and radiation-sensitive resin compounds JSR Corporation (JP) 2001-10-10 EP disclosed
US-6184171-B1 CATALYST COMPOSITION COMPRISES AN ANIONIC METALLOID SILANE MODIFIED INORGANIC OXIDE AND THE CATIONIC REMNANT OF A TRANSITION METAL BIDENTATE OR TRIDENTATE COMPOUND W.R. GRACE & CO. -CONN 2001-02-06 US disclosed
JP-S6390534-A ALKALI-SOLUBLE LADDER SILICONE POLYMER HITACHI LTD 1988-04-21 JP disclosed
US-4179511-A Antibacterial 3-(5-tetrazolyl) penam compounds PFIZER INC. (US) 1979-12-18 US disclosed
US-4143039-A ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS PFIZER INC. (US) 1979-03-06 US disclosed
US-4115385-A PENICILLINS PFIZER INC. (US) 1978-09-19 US disclosed
US-3994939-A BACTERICIDES PFIZER INC. (US) 1976-11-30 US disclosed