Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20652081 | 0.86 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11261240 | 0.84 | ALDH1A1 (0.59) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL14817233 | 0.84 | ALDH1A1 (0.63) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL23311701 | 0.83 | ALDH1A1 (0.58) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11258356 | 0.82 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11249082 | 0.80 | ALDH1A1 (0.54) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL26242316 | 0.80 | ALDH1A1 (0.54) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11244958 | 0.78 | ALDH1A1 (0.51) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL9561102 | 0.77 | ALDH1A1 (0.63) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL33121 | 0.76 | ALDH1A1 (0.68) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337501-B1 | PROCESS FOR PREPARING 1-INDANONES | AKZO NOBEL NV (NL) | 2006-12-20 | — | — | EP | disclosed |
| EP-1337501-A1 | PROCESS FOR PREPARING 1-INDANONES | Akzo Nobel N.V. (NL) | 2003-08-27 | — | — | EP | disclosed |
| US-6548710-B2 | Reacting ketone compound with chlorinating agent, followed by reaction with a friedel-crafts catalyst to produce 1-indanone compound | AKZO NOBEL N.V. (NL) | 2003-04-15 | — | — | US | disclosed |
| US-20020077507-A1 | Process for preparing 1-indanones | AKZO NOBEL N.V. (NL) | 2002-06-20 | — | — | US | disclosed |
| WO-2002036537-A1 | PROCESS FOR PREPARING 1-INDANONES | AKZO NOBEL N.V. (NL) | 2002-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077507-A1 | Process for preparing 1-indanones | CYP1A1, CYP2F1, CYP1B1 | ALDH1A1 240/4885RAB9A 2795/4885NPC1 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.