Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20652081 | 0.86 | ALDH1A1 (0.61) | ALDH1A1SMYD3NPC1RAB9AMAPT | |
| SCHEMBL11261240 | 0.84 | ALDH1A1 (0.59) | ALDH1A1SMYD3NPC1RAB9AMAPT | |
| SCHEMBL14817233 | 0.84 | ALDH1A1 (0.63) | ALDH1A1SMYD3NPC1RAB9AMAPT | |
| SCHEMBL5716811 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMYD3NPC1RAB9AMAPT | |
| SCHEMBL11258356 | 0.82 | ALDH1A1 (0.61) | ALDH1A1SMYD3NPC1RAB9AMAPT | |
| SCHEMBL11249082 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMYD3NPC1RAB9AMAPT | |
| SCHEMBL26242316 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMYD3NPC1RAB9AMAPT | |
| SCHEMBL11244958 | 0.78 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9561102 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL1466022 | 0.76 | NPC1 (0.67) | ALDH1A1SMYD3NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210121584-A1 | TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES | CORNELL UNIVERSITY (US) | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210121584-A1 | TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES | VHL, GLS, GPER1 | ALDH1A1 1271/4885SMYD3 4768/4885NPC1 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.