Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571770 | 1.00 | TSHR (0.54) | TSHRNPSR1BLMAPOBEC3AHTT | |
| SCHEMBL1572868 | 0.88 | BLM (0.62) | TSHRNPSR1BLMHTTHPGD | |
| SCHEMBL1572866 | 0.88 | BLM (0.62) | TSHRNPSR1BLMHTTHPGD | |
| SCHEMBL8824090 | 0.82 | BLM (0.64) | TSHRNPSR1BLMHPGDMAPT | |
| SCHEMBL1892421 | 0.80 | TSHR (0.49) | TSHRNPSR1APOBEC3AHTTAPOBEC3G | |
| Dimethylformamide SCHEMBL28191624 | 0.78 | BLM (0.51) | TSHRNPSR1BLMHTTHPGD | |
| Dimethylformamide SCHEMBL28191620 | 0.78 | BLM (0.51) | TSHRNPSR1BLMHTTHPGD | |
| SCHEMBL11135068 | 0.78 | BLM (0.67) | TSHRNPSR1BLMMAPTALDH1A1 | |
| SCHEMBL11135072 | 0.78 | BLM (0.67) | TSHRNPSR1BLMMAPTALDH1A1 | |
| SCHEMBL6774969 | 0.77 | TSHR (0.48) | TSHRNPSR1APOBEC3AHTTAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9748487-B2 | Polymers based on naphthodiones | BASF SE (DE) | 2017-08-29 | — | — | US | disclosed |
| EP-2917304-B1 | POLYMERS BASED ON NAPHTHODIONES | BASF SE (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-20160049588-A1 | POLYMERS BASED ON NAPHTHODIONES | BASF SE (DE) | 2016-02-18 | — | — | US | disclosed |
| EP-2917304-A2 | POLYMERS BASED ON NAPHTHODIONES | BASF SE (DE) | 2015-09-16 | — | — | EP | disclosed |
| WO-2014072292-A2 | POLYMERS BASED ON NAPHTHODIONES | BASF SE (DE) | 2014-05-15 | — | — | WO | disclosed |
| WO-2012017005-A2 | POLYMERS BASED ON BENZODIONES | BASF SE (DE) | 2012-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160049588-A1 | POLYMERS BASED ON NAPHTHODIONES | CCND2, CCND1, PCNA | TSHR 3050/4885NPSR1 1486/4885BLM 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.