Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | PKM | P14618 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | GLA | P06280 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5912239 | 0.87 | ALDH1A1 (0.76) | ALDH1A1KDM4EGAAPKMHPGD | |
| SCHEMBL22271486 | 0.80 | KDM4E (0.66) | ALDH1A1KDM4EGAAPKMHPGD | |
| SCHEMBL14740159 | 0.80 | KDM4E (0.66) | ALDH1A1KDM4EGAAPKMHPGD | |
| SCHEMBL9129589 | 0.79 | KDM4E (0.65) | ALDH1A1KDM4EGAAPKMHPGD | |
| SCHEMBL9384146 | 0.78 | KDM4E (0.64) | ALDH1A1KDM4EGAAPKMHPGD | |
| SCHEMBL9130281 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAPKMHPGD | |
| SCHEMBL199891 | 0.77 | GAA (0.68) | ALDH1A1KDM4EGAAPKMHPGD | |
| SCHEMBL9129179 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAPKMHPGD | |
| SCHEMBL19533498 | 0.76 | KDM4E (0.61) | ALDH1A1KDM4EGAAPKMHPGD | |
| SCHEMBL28903304 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAAPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| US-6818772-B2 | DIETETICS, SLEEP DISORDERS, EATING DISORDERS, SEXUAL DISORDERS, CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | ABBOTT LABORATORIES | 2004-11-16 | — | — | US | disclosed |
| US-20030229119-A1 | Antagonists of melanin concentrating hormone effects on the melanin concetrating hormone receptor | ABBVIE INC. | 2003-12-11 | — | — | US | disclosed |
| WO-2003070244-A1 | ANTAGONIST OF MELANIN CONCENTRATING HORMONE AND THEIR USES | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5387588-A | Antiulcer agents | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-02-07 | — | — | US | disclosed |
| EP-0326981-B1 | 4-Oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide derivatives, their preparation, medicaments containing them and their preparation | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1994-11-09 | — | — | EP | disclosed |
| US-5252572-A | Antiulcer agent | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-10-12 | — | — | US | disclosed |
| US-5158951-A | Pyridopyrimidine derivatives useful in treatment of ulcers | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYAR RT. (HU) | 1992-10-27 | — | — | US | disclosed |
| EP-0326981-A2 | 4-Oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide derivatives, their preparation, medicaments containing them and their preparation | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1989-08-09 | — | — | EP | disclosed |
| US-4192944-A | ANTIANAPHYLACTIC | BRISTOL-MYERS COMPANY (US) | 1980-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229119-A1 | Antagonists of melanin concentrating hormone effects on the melanin concetrating hormone receptor | MCHR1, MCHR2, MC1R | ALDH1A1 2373/4885KDM4E 2065/4885GAA 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.