Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030966 | 0.90 | P2RY12 (0.66) | P2RY12ALOX15 | |
| SCHEMBL20460281 | 0.86 | ALOX15 (0.68) | P2RY12ALOX15 | |
| SCHEMBL2073956 | 0.85 | ALOX15 (0.71) | P2RY12ALOX15 | |
| SCHEMBL20460357 | 0.85 | ALOX15 (0.66) | P2RY12ALOX15MEN1KMT2A | |
| SCHEMBL23710419 | 0.84 | ALOX15 (0.64) | P2RY12ALOX15 | |
| SCHEMBL20460301 | 0.84 | ALOX15 (0.64) | P2RY12ALOX15 | |
| SCHEMBL20460325 | 0.82 | ALOX15 (0.63) | P2RY12ALOX15 | |
| SCHEMBL20460330 | 0.81 | P2RY12 (0.66) | P2RY12ALOX15 | |
| SCHEMBL13035843 | 0.81 | ALOX15 (0.73) | P2RY12ALOX15 | |
| SCHEMBL13075989 | 0.81 | ALOX15 (0.77) | P2RY12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| US-20050215495-A1 | Macrolide antibiotics | ALIHODZIC SULEJMAN | 2005-09-29 | — | — | US | disclosed |
| US-20040077557-A1 | Macrolide antibiotics | GLAXO GROUP LIMITED (GB) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215495-A1 | Macrolide antibiotics | IL1R1, MRPL12, RPS21 | P2RY12 3365/4885ALOX15 2590/4885MEN1 2872/4885 |
| US-20040077557-A1 | Macrolide antibiotics | MALT1, MRPL21, IL1R1 | P2RY12 4281/4885ALOX15 2244/4885MEN1 2870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.