Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CXCR6 | O00574 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717888 | 0.90 | THRB (0.39) | KMT2APKMMEN1MAPTALDH1A1 | |
| SCHEMBL5718210 | 0.88 | KMT2A (0.38) | KMT2APKMMEN1MAPTALDH1A1 | |
| SCHEMBL5718089 | 0.87 | KMT2A (0.36) | KMT2APKMMRGPRX4MEN1MAPT | |
| SCHEMBL5717838 | 0.87 | KMT2A (0.38) | KMT2APKMMRGPRX4MEN1MAPT | |
| SCHEMBL5722532 | 0.85 | KMT2A (0.38) | KMT2APKMMEN1MAPTALDH1A1 | |
| SCHEMBL5722616 | 0.85 | THRA (0.40) | KMT2APKMMEN1MAPTALDH1A1 | |
| SCHEMBL4924842 | 0.84 | KMT2A (0.39) | KMT2APKMMEN1MAPTALDH1A1 | |
| SCHEMBL4358268 | 0.83 | PDE4A (0.38) | KMT2APKMMEN1LMNAHPGD | |
| SCHEMBL5717750 | 0.82 | THRA (0.36) | KMT2AMEN1GAACYP1A2CYP3A4 | |
| SCHEMBL5717921 | 0.82 | THRA (0.34) | KMT2APKMMRGPRX4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732533-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092317-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2005-10-06 | — | — | WO | disclosed |