Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891127 | 0.86 | CYP2A6 (0.46) | CYP2A6LOXL2MAOAMAOBCYP11B1 | |
| SCHEMBL2037665 | 0.84 | KLK8 (0.36) | POLB | |
| SCHEMBL578310 | 0.82 | CYP2A6 (0.50) | CYP2A6LOXL2MAOAMAOBCYP11B1 | |
| SCHEMBL10924475 | 0.80 | CYP2A6 (0.47) | CYP2A6LOXL2MAOAMAOBCYP11B1 | |
| SCHEMBL5041135 | 0.80 | GLA (0.63) | MAOBCYP11B1CYP11B2ALDH1A1CYP19A1 | |
| SCHEMBL7043203 | 0.78 | PTK2 (0.39) | MAOBALDH1A1RAB9AMAPT | |
| SCHEMBL8958940 | 0.76 | AGXT (0.40) | CYP2A6RAB9AMAPTTSHR | |
| SCHEMBL13624524 | 0.76 | SMN1; SMN2 (0.44) | CYP2A6ALDH1A1RAB9AMAPTPOLB | |
| SCHEMBL10397175 | 0.76 | CYP2A6 (0.55) | CYP2A6LOXL2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL9803879 | 0.75 | LOXL2 (0.38) | CYP2A6LOXL2MAOBCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391731-A1 | PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF | LIANGJIANG MEDICINE CO., LTD. (CN) | 2023-12-07 | — | — | US | disclosed |
| EP-1210476-B1 | MIXTURES OF FLUORESCENT WHITENING AGENTS | CIBA SC HOLDING AG (CH) | 2006-06-14 | — | — | EP | disclosed |
| US-6719922-B1 | ISOMERS OF CYANO-SUBSTITUTED 1,4-BIS-STYRYLBENZENES; SYNTHETIC POLYESTER FIBERS | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-04-13 | — | — | US | disclosed |
| EP-1210476-A1 | MIXTURES OF FLUORESCENT WHITENING AGENTS | Ciba SC Holding AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| EP-1153011-A1 | BIS-STYRYLBIPHENYL COMPOUNDS | Ciba SC Holding AG (CH) | 2001-11-14 | — | — | EP | disclosed |
| WO-2001018301-A1 | MIXTURES OF FLUORESCENT WHITENING AGENTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-15 | — | — | WO | disclosed |
| WO-2000047550-A1 | BIS-STYRYLBIPHENYL COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-08-17 | — | — | WO | disclosed |
| EP-0238446-B1 | Mixtures of optical brighteners | CIBA GEIGY AG (CH) | 1995-11-15 | — | — | EP | disclosed |
| US-4891153-A | Mixtures of fluorescent whitening agents | CIBA-GEIGY CORPORATION (US) | 1990-01-02 | — | — | US | disclosed |
| US-4778622-A | Mixtures of fluorescent whitening agents | CIBA-GEIGY CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0238446-A1 | Mixtures of optical brighteners | CIBA-GEIGY AG (CH) | 1987-09-23 | — | — | EP | disclosed |
| US-4016195-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-3957846-A | OPTICAL BRIGHTENERS, LACQUERS, SYNTHETIC FIBERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391731-A1 | PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF | GRPR, SLC2A8, HPGDS | CYP2A6 1251/4885LOXL2 1669/4885MAOA 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.