Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802445 | 0.91 | GAA (0.54) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8708250 | 0.85 | GAA (0.64) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8808451 | 0.85 | GAA (0.49) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8801247 | 0.85 | GAA (0.49) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL571262 | 0.84 | GAA (0.68) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8809032 | 0.81 | GAA (0.49) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8810586 | 0.81 | GAA (0.49) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8705625 | 0.81 | ALDH1A1 (0.63) | GAAALDH1A1HPGDGLAMEN1 | |
| SCHEMBL9726098 | 0.79 | GAA (0.47) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8801493 | 0.78 | GAA (0.43) | GAAALDH1A1HPGDGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017005-A2 | POLYMERS BASED ON BENZODIONES | BASF SE (DE) | 2012-02-09 | — | — | WO | disclosed |