Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802445 | 0.91 | GAA (0.54) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8708250 | 0.85 | GAA (0.64) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL571812 | 0.85 | GAA (0.49) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8801247 | 0.85 | GAA (0.49) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL571262 | 0.84 | GAA (0.68) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8809032 | 0.81 | GAA (0.49) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8810586 | 0.81 | GAA (0.49) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8705625 | 0.81 | ALDH1A1 (0.63) | GAAALDH1A1HPGDGLAMAPT | |
| SCHEMBL9726098 | 0.79 | GAA (0.47) | GAAALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL3536195 | 0.78 | ALDH1A1 (0.40) | GAAALDH1A1HPGDGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502278-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1997-03-05 | — | — | EP | disclosed |
| US-5374724-A | Process for the preparation of substituted acetic acids | ZENECA, LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| US-5189181-A | Process for preparation 2,6-dihydrobenzo[1:26, 4:5-6]-difuran dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-23 | — | — | US | disclosed |
| EP-0502278-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1992-09-09 | — | — | EP | disclosed |