Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GPX4 | P36969 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL9311898 | 0.81 | HDAC11 (0.52) | ALDH1A1TSHRHDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL15167368 | 0.79 | TSHR (0.53) | MEN1KMT2ATSHRHDAC3HDAC1 | |
| SCHEMBL3278936 | 0.78 | MEN1 (0.49) | NPC1ALDH1A1RAB9APAX8TP53 | |
| Adipic Acid SCHEMBL5180701 | 0.77 | TSHR (0.51) | MEN1KMT2ATSHRHDAC3HDAC1 | |
| Adipic Acid SCHEMBL1506376 | 0.77 | TSHR (0.51) | MEN1KMT2ATSHRHDAC3HDAC1 | |
| Azelaic Acid SCHEMBL28393484 | 0.74 | HDAC3 (0.50) | NPC1RAB9AMEN1KMT2ATSHR | |
| Dodecanoate SCHEMBL28418541 | 0.74 | GPR84 (0.61) | ALDH1A1MEN1KMT2ATSHRHDAC11 | |
| M-Xylene SCHEMBL3694363 | 0.74 | PARP1 (0.47) | KMT2ATSHRHDAC3HDAC1HDAC2 | |
| Sebacic Acid SCHEMBL28395117 | 0.74 | HDAC3 (0.50) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL1250870 | 0.73 | MAPT (0.53) | ALDH1A1TP53HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015008-A4 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1015008-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998034632-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-08-13 | — | — | WO | disclosed |