Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398253 | 0.91 | HTR7 (0.51) | CDC7HTR7ALDH1A1MAPTMEN1 | |
| SCHEMBL29507010 | 0.82 | PRKCI (0.70) | PRKCIALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5718697 | 0.82 | PRKCI (0.70) | PRKCIALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL398452 | 0.82 | PRKCI (0.70) | PRKCIALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL397061 | 0.81 | PRKCI (0.68) | PRKCIALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1098394 | 0.78 | CYP19A1 (0.51) | PRKCIHTR7ALDH1A1MAPTMEN1 | |
| SCHEMBL5718703 | 0.75 | PRKCI (0.52) | PRKCIALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8686325 | 0.73 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL29936240 | 0.73 | ALDH1A1 (0.43) | HTR7ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL26697740 | 0.73 | ALDH1A1 (0.43) | HTR7ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986633-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Summit Corporation Plc (GB) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007091106-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2007-08-16 | — | — | WO | disclosed |