Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 13/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720219 | 0.82 | POLB (0.51) | TRPM8ALDH1A1POLBTDP1SMN1; SMN2 | |
| SCHEMBL5720266 | 0.73 | HSD17B10 (0.40) | MEN1KMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL12539260 | 0.72 | TRPM8 (0.62) | TRPM8 | |
| SCHEMBL85862 | 0.72 | TSHR (0.46) | MEN1KMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL7203762 | 0.72 | TSHR (0.46) | MEN1KMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL7209322 | 0.72 | TSHR (0.46) | MEN1KMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL829752 | 0.71 | TSHR (0.60) | MEN1KMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL829751 | 0.71 | TSHR (0.60) | MEN1KMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL835910 | 0.71 | TSHR (0.60) | MEN1KMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL829750 | 0.71 | TSHR (0.60) | MEN1KMT2AHSD17B10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668007-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026163-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-24 | — | — | WO | disclosed |