Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPM1B | O75688 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85862 | 1.00 | TSHR (0.46) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL7203762 | 1.00 | TSHR (0.46) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL5719777 | 0.92 | PPM1B (0.46) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL16402657 | 0.92 | PPM1B (0.46) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL85522 | 0.92 | PPM1B (0.46) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL17145410 | 0.90 | TSHR (0.42) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL1862124 | 0.84 | TSHR (0.45) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL17830448 | 0.80 | CTSL (0.41) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL8213451 | 0.79 | ALDH1A1 (0.47) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL2387688 | 0.78 | TSHR (0.55) | TSHRPPM1BPTPN1PPP1CCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632028-B1 | OPTICALLY ACTIVE 2-NITROIMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATE FOR PRODUCING THE SAME | POLA CHEM IND INC (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5532380-A | RADIOSENSITIZERS FOR CANCER THERAPY; PURE ENANTIOMORPHS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0632028-A1 | OPTICALLY ACTIVE 2-NITROIMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATE FOR PRODUCING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1995-01-04 | — | — | EP | disclosed |