Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1949230 | 0.94 | BACE1 (0.41) | BACE1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL16825914 | 0.94 | OPRD1 (0.45) | BACE1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL24940830 | 0.88 | MEN1 (0.43) | BACE1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL30732662 | 0.87 | MEN1 (0.42) | BACE1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL27139196 | 0.87 | OPRD1 (0.43) | BACE1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL743654 | 0.87 | TACR1 (0.43) | BACE1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL4475409 | 0.87 | TGM2 (0.42) | MEN1KMT2A | |
| SCHEMBL30706936 | 0.87 | PPIA (0.41) | BACE1MEN1KMT2ASYK | |
| SCHEMBL4780264 | 0.85 | NPFFR1 (0.48) | BACE1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL4780268 | 0.85 | NPFFR1 (0.48) | BACE1OPRD1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1630162-A1 | 2-AMINOQUINOLINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-03-01 | — | — | EP | disclosed |