SCHEMBL5721238

SCHEMBL5721238

CCCCC1=Cc2c(ccc(CC)c2-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1[Zr](Cl)Cl

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ICMT O60725 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721484 0.91 RXRA (0.33) RXRARXRBRXRG
SCHEMBL5721725 0.90
SCHEMBL5721334 0.88 CTSS (0.31) RXRARXRBRXRG
SCHEMBL5721302 0.86
SCHEMBL5608834 0.85
SCHEMBL5721378 0.84 CNR1 (0.30)
SCHEMBL5721748 0.84
SCHEMBL5721636 0.84 RXRA (0.30) RXRARXRB
SCHEMBL5721688 0.83 RXRA (0.32) RXRARXRBRXRG
SCHEMBL5721653 0.82 RXRA (0.31) RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-A1 Metallocenes and catalyst compositions derived therefrom Exxonmobil Chemical Patents Inc. (US) 2006-03-29 EP disclosed