Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721304 | 0.90 | RXRA (0.35) | RXRARXRBRXRGIKBKBDRD2 | |
| SCHEMBL5721651 | 0.84 | RXRA (0.35) | RXRARXRBRXRGIKBKBICMT | |
| SCHEMBL5721827 | 0.84 | RXRA (0.35) | RXRARXRBRXRGIKBKBICMT | |
| SCHEMBL5721553 | 0.83 | RXRA (0.34) | RXRARXRBRXRGICMTDRD2 | |
| SCHEMBL5721387 | 0.83 | IKBKB (0.40) | RXRARXRBRXRGIKBKBCNR1 | |
| SCHEMBL5721760 | 0.82 | CNR1 (0.37) | RXRARXRBRXRGDRD2HTR2A | |
| SCHEMBL5721400 | 0.81 | HEXA (0.33) | — | |
| SCHEMBL5721646 | 0.81 | RXRA (0.33) | RXRARXRBRXRGICMTAKR1C3 | |
| SCHEMBL5721518 | 0.81 | ICMT (0.33) | RXRARXRBRXRGICMTDRD2 | |
| SCHEMBL5721623 | 0.81 | RXRA (0.33) | RXRARXRBRXRGICMTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |